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US: Marijuana-based drug gets positive review from FDA - WCMH

Found: Tue Apr 17 08:47:40 2018 PDT
Webpage: http://www.nbc4i.com/news/u-s-world/mariju... [translate]
Newshawk: http://drugpolicycentral.com/bot/


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Marijuana-based drug gets positive review from FDA - WCMH Marijuana-based drug gets positive review from FDA - WCMH

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Posted: Apr 17, 2018 10:47 AM EDT

Updated: Apr 17, 2018 10:47 AM EDT

Copyright 2018 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

FILE - This May 23, 2017, file photo shows GW Pharmaceuticals' Epidiolex, a medicine made from the marijuana plant but without TCH. (AP Photo/Kathy Young, File)

Copyright 2018 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

FILE - This May 23, 2017, file photo shows GW Pharmaceuticals' Epidiolex, a medicine made from the marijuana plant but without TCH. (AP Photo/Kathy Young, File)

WASHINGTON (AP) - A closely watched medicine made from the marijuana plant reduces seizures in children with severe forms of epilepsy and warrants approval in the United States, health officials said Tuesday.

British drugmaker GW Pharmaceuticals is seeking permission to sell its purified form of an ingredient found in cannabis - one that doesn't get users high - as a medication for rare, hard-to-treat seizures in children. If successful, the company's liquid formula would be the first government-approved drug derived from the cannabis plant in the U.S.

The Food and Drug Administration's approval would technically limit the treatment to a small group of epilepsy patients. But doctors would have the option to prescribe it for other uses and it could spur new pharmaceutical research and interest into other cannabis-based products. Man-made versions of a different marijuana ingredient have previously been approved for other purposes.

The FDA posted its review of the experimental medication Epidiolex ahead of a public meeting Thursday when a panel of outside experts will vote on the medicine's safety and effectiveness. It's a non-binding recommendation that the FDA will consider in its final decision by late June.

Patients taking the treatment had fewer seizures, according to the FDA's internal review posted online. Scientists concluded that GW Pharmaceutical's submission "appears to support approval" despite some potential side effects including risks of liver injury.

More than two dozen states allow marijuana use for a variety of ailments, but the FDA has not approved it for any medical use. In 2016, the agency recommended against easing federal restrictions on marijuana. The U.S. continues to classify marijuana as a high-risk substance with no medical use, alongside other illicit drugs like heroin and LSD.

For years, desperate patients and parents have pushed for wider access to medical marijuana products for a host of conditions including pain, post-traumatic stress disorder and epilepsy, with only anecdotal stories and limited studies on their side.

But studies conducted by GW Pharmaceuticals have begun to change that picture.

Across three studies involving more than 500 patients, Epidiolex generally cut the number of monthly seizures by about 40 percent, compared with reductions between 15 and 20 percent for patients taking a dummy medicine.

Most patients in the study were already taking at least three other medications to try and control their seizures.

Epidiolex is essentially a pharmaceutical-grade version of cannabidiol, or CBD oil, which some parents have used for years to treat children with epilepsy. CBD is one of more than 100 chemicals found in the cannabis plant and it doesn't contain THC, the ingredient that gives marijuana its mind-altering effect.

CBD oil is currently sold online and in specialty shops across the U.S., though its legal status remains murky. Most producers say their oil is made from hemp, a plant in the cannabis family that contains little THC and can be legally farmed in a number of states for clothing, food and other uses.

A doctor who treats children with epilepsy says it's important to have an FDA-approved version of CBD.

"I think it needs to be approved because everyone is using it across the internet without knowing the safety ... and no one is watching the interactions with other drugs," said Dr. Joan Conry of Children's National Health System in Washington, who was not involved in the studies.

Conry and other researchers say it's not yet clear why CBD reduces seizures in some patients.

GW Pharmaceuticals makes its drug from cannabis plants that are specially bred to contain high levels of CBD. It's seeking approval for two rare forms of childhood epilepsy - Dravet and Lennox-Gastaut syndromes.

Common side effects included diarrhea, vomiting, fatigue and sleep problems. FDA reviewers flagged a more serious issue with potential liver injury, but said doctors could manage the risk by monitoring patients' enzyme levels.

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analysis of article text


prohibitionist hits:0 government drug warrior (prohibition_agency) hits:0 propaganda (drugwar_propaganda) hits:22 legalization hits:0 drug_reformer hits:0 reform_referenda hits:0 cannabis hits:32 stimulant hits:0 narcotic hits:1 hallucinogen hits:1
    prohibitionist     prohibition_agency     drugwar_propaganda     legalization     drug_reformer
    reform_referenda     cannabis     stimulant     narcotic     hallucinogen
                        
                        


incarceration/prison mentioned? yes .

propaganda analysis


explicit prohibition propaganda (explicit_propaganda) hits:0 hated group (propaganda_theme1) hits:0 madness, violence, illness (propaganda_theme2) hits:11 survival of society (propaganda_theme3) hits:0 gateway, use is abuse (propaganda_theme4) hits:3 children (propaganda_theme5) hits:8 demonize, war, epidemic (propaganda_theme6) hits:0 total prohibition (propaganda_theme7) hits:0 dissent opposed (propaganda_theme8) hits:0
EXP - explicit prohibition propaganda (explicit_propaganda) GRP - hated group (propaganda_theme1) MAD - madness, violence, illness (propaganda_theme2)
SOC - survival of society (propaganda_theme3) USE - gateway, use is abuse (propaganda_theme4) KID - children (propaganda_theme5)
WAR - demonize, war, epidemic (propaganda_theme6) TOT - total prohibition (propaganda_theme7) DIS - dissent opposed (propaganda_theme8)



conceptevidencehitslinks
 drug of abuse implied / mentioned

drug related
[news] [concept]

illegal drugs  
drugwar_propaganda : a drug war propaganda event, campaign release, slogan, or themepropaganda

drugwar propaganda
[news] [concept]

propaganda theme2 propaganda theme5 propaganda theme4 Why Are Americans So Easy to Manipulate? (Bruce E Levine, 2012)
Classic Modern Drug Propaganda
Themes in Chemical Prohibition
Drug War Propaganda (kindle edition)
propaganda_theme2 : drug war propaganda theme: madness, violence, illness caused by drugsmadness, violence, illness

propaganda theme2 70%
[news] [concept]

"murder" "injury" "seizures" "death" "problems"11Madness Crime Violence Illness (propaganda theme 2)
drugwarfacts.org/crime.htm
drugwarfacts.org/causes.htm
Distortion 18: Cannabis and Mental Illness
No, marijuana use doesn't lower your IQ (10/2014)
 use is abuse

use is abuse
[news] [concept]

"marijuana use"1Use is Abuse (propaganda theme 4)
drugwarfacts.org/addictiv.htm
 gateway

gateway 60%
[news] [concept]

"with other drugs" "leads to"2Use is Abuse, Gateway (propaganda theme 4)
drugwarfacts.org/gatewayt.htm
Distortion 7: Gateway
propaganda_theme4 : drug war propaganda theme: all use is abuse, gatewaygateway, use is abuse

propaganda theme4
[news] [concept]

use is abuse gateway Use is Abuse, Gateway (propaganda theme 4)
propaganda_theme5 : drug war propaganda theme: children corrupted by drugschildren

propaganda theme5 60%
[news] [concept]

"child" "children" "parents"8Children Corrupted (propaganda theme 5)
drugwarfacts.org/adolesce.htm
Think of the children
 drug of abuse

illegal drugs
[news] [concept]

cannabis various illegal drugs hallucinogen narcotic  
 drugs
[news] [concept]
various drugs  
hallucinogen : the hallucinogens or psychedelics; also disassociativeshallucinogen
[news] [concept]
psychedelic MAPS.org/
erowid.org/
lycaeum.org/
mapinc.org/hallucinogens.htm
Wikipedia: Psychedelics, dissociatives and deliriants
 psychoactive chemical

chemicals
[news] [concept]

alcohol heroin LSD opiate erowid.org/chemicals/chemicals.s...
 psychoactive plant

plants
[news] [concept]

cannabis erowid.org/plants/plants.shtml
 euphoric depressant
[news] [concept]
heroin opiate  
 analgesic
[news] [concept]
heroin opiate  
 psychedelic
[news] [concept]
LSD maps.org/
Psychedelic
psychedelic-library.org/
 intoxicant
[news] [concept]
cannabis  
 depressant intoxicant
[news] [concept]
alcohol  
 hemp
[news] [concept]
"hemp"1mapinc.org/hemp.htm
drugwarfacts.org/hemp.htm
medical_cannabis : cannabis for medical usemedical cannabis
[news] [concept]
"medical marijuana" "medicine made from the marijuana"4medicalmarijuanaprocon.org/
drugwarfacts.org/medicalm.htm
mapinc.org/mmj.htm
mapinc.org/find?253
Cannabis Treats Anxiety, Depression And Activates Pathways That Regulate Emotional Behavior (2014)
The Flower (video cartoon)
 narcotic
[news] [concept]
opiate Managing Pain
opiate : a substance derived from the opium poppyopiate
[news] [concept]
heroin Managing Pain
 alcohol
[news] [concept]
"drunk"2Stanton Peele Addiction Web Site
drugwarfacts.org/alcohol.htm
Pot Threatens Booze Profits
 heroin
[news] [concept]
"heroin"1google.com/search?q=Alfred+McCoy...
mapinc.org/heroin.htm
drugwarfacts.org/heroin.htm
Managing Pain
 lysergic acid diethylamide

LSD
[news] [concept]

"LSD"1erowid.org/chemicals/lsd/
cannabis : cannabis (marijuana) product or usecannabis
[news] [concept]
"Marijuana-based" "marijuana" "cannabis" "cannabis-based" "THC" "cannabidiol" "CBD" medical cannabis hemp27Cannabis: Religious and Spiritual Uses
Cannabis-Driving Studies
MAPInc.org Cannabis Link DB
medicalmarijuanaprocon.org
cannabisculture.com
Schaffer Library: Marijuana
drugwarfacts.org/marijuan.htm
mapinc.org/pot.htm
U.S. Prisons Thriving on Jim Crow Marijuana Arrests (2013)
 various drugs
[news] [concept]
"Pharmaceuticals" "pharmaceutical" "pharmaceutical-grade" "drug" "drugs" "drugmaker"25 
 various illegal drugs
[news] [concept]
"illicit drugs" "mind-altering"2mapinc.org
drugwarfacts.org
DEA's Drugs of Abuse booklet
drugwarfacts.org/drugtest.htm
 incarceration
[news] [concept]
"jail"3Prison Hell in America (Stephen Lendman, Oct. 2011)
Understanding the U.S. Torture State
this is what a police state looks like
Torture and the United States
drugwarfacts.org/cms/Prisons and...
aclu.org/combating-mass-incarcer...
november.org
mapinc.org/prison.htm
hermes-press.com/prisons drugs.htm
US Official Prison Policy: Encourage Men's Rape (2014)
Profit Driven Prison Industrial Complex (2012)
The Top Five Special Interest Groups Lobbying To Keep Marijuana Illegal
Sing a Little Louder
Prison Rape Widely Ignored by Authorities
thedailysheeple.com/prisons-are-...
Push Back Against Drug War Profiteering with Jury Nullification
 youth 60%
[news] [concept]
propaganda theme5 ssdp.org/
mapinc.org/youth.htm
 school
[news] [concept]
"school" "colleges" "University"3ssdp.org/
 aggrandizing government

aggrandizement
[news] [concept]

"officials" "experts"2Statism: the Most Dangerous Religion (2014 video)
What is Statism?
Conservapedia: Statism
Wikipedia: Statolatry
lewrockwell.com/2014/07/thomas-d...
Bought Priesthood
Worship of the U. S. Government (2011)
Bureaucratic Thrust
Tyranny of Experts
The Threat of Authority (2012)
The Media As Enablers of Government Lies
The Statist Mindset (Jacob Hornberger, 2011)
Thinking Critically about Experts and Authority
'Scientific' evidence for FDA-approved drugs isn't so scientific, it turns out (2014)
The Intellectual Gravy Train (2015)
 mainstream (controlled) media

msm
[news] [concept]

mockingbird Mainstream Media
whowhatwhy.org/2014/04/09/media-...
archive.lewrockwell.com/orig14/a...
Michael Levine, Mainstream Media: The Drug War Shills
beforeitsnews.com/alternative/20...
Mainstream Media: The Most Significant Threat To Freedom
msm.rt.com/
sputniknews.com/europe/20160225/...
 Mockingbird / Wurlitzer; US intel-controlled media

mockingbird
[news] [concept]

"NBC" assoc press2Operation Mockingbird - Mighty Wurlitzer
carlbernstein.com/magazine cia a...
US Media Conceals News (2013)
Two of the Largest American Newspapers Opine in Favor of Allowing States to Legalize Marijuana (2012)
reuters.com/article/2014/07/27/u...
https://web.archive.org/web/2013...
Propaganda 101: Operation Mockingbird Continues (2015)
 assoc press
[news] [concept]
"Associated Press" "AP"4carlbernstein.com/magazine cia a...
Associated Press (AP) - Mockingbird / Wurlitzer

st:0.01 fo:0 s:0.01 d:0 c:0 db:0.113 a:0.52 m:0.47 t:1.44 (f)


text of article used for CRITICAL ANALYSIS, under FAIR USE provisions of the Copyright Act of 1976, 17 U.S.C. § 107, et al.


media charts

Bot's analysis of: "The Dangers and Consequences of Marijuana Abuse" the U.S. Department of Justice Drug Enforcement Administration (DEA) Demand Reduction Section, May 2014
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Drug War
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A review and analysis of modern prohibition rhetoric

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    article tags



     

    assoc_press concept - AP - Associated Press - long linked with "Mighty Wurlitzer" intel ops like, "Operation Mockingbird"
    mockingbird concept - documented US intel controlled media: newspapers, tv, radio - various press associated with known intel ops such as, "Operation Mockingbird", "Mighty Wurlitzer", etc.
    msm concept - mainstream media - corporate, government controlled press: newspaper, tv, radio, websites; press associated with known intel ops such as, "Operation Mockingbird", "Mighty Wurlitzer", Tavistock Institute, etc.
    aggrandizement concept - terms of aggrandizement (of government)
    school concept
    youth concept
    incarceration concept - Prisons, Jails and Probation
    various_illegal_drugs concept - general terms for illegal drugs
    various_drugs concept - general terms for drugs
    cannabis concept - cannabis (marijuana) product or use
    cannabis
    LSD concept - LSD is the best known and most researched psychedelic. It is the standard against which all other psychedelics are compared. It is active at extremely low doses and is most commonly available on blotter or in liquid form. (d-lysergic acid diethylamide)
    heroin concept - heroin, heroine, diamorphine
    alcohol concept - ethyl alcohol for intoxication
    opiate concept - a substance derived from the opium poppy
    opiate
    narcotic concept - a drug that dulls senses, relieves pain, induces sleep
    medical_cannabis concept - cannabis for medical use
    medical_cannabis
    hemp concept - industrial hemp (for food, fuel, fiber, etc.)
    depressant_intoxicant concept
    intoxicant concept
    psychedelic concept
    analgesic concept
    euphoric_depressant concept
    plants concept - Plants listed in this section are those which have been used by humans for their mind- or emotion-altering properties.
    chemicals concept - Psychoactive Chemicals are chemicals which have mind- or emotion-altering properties.
    hallucinogen concept - the hallucinogens or psychedelics; also disassociatives
    hallucinogen
    drugs concept
    illegal_drugs concept - drugs of abuse, so-called
    propaganda_theme5 concept - drug war propaganda theme: children corrupted by drugs
    propaganda_theme5
    propaganda_theme4 concept - drug war propaganda theme: all use is abuse, gateway
    propaganda_theme4
    gateway concept - drug war propaganda theme: gateway
    use_is_abuse concept - drug war propaganda theme: all use is abuse
    propaganda_theme2 concept - drug war propaganda theme: madness, violence, illness caused by drugs
    propaganda_theme2
    drugwar_propaganda concept - a drug war propaganda event, campaign release, slogan, or theme
    drugwar_propaganda
    drug_related concept - related to illegal drugs and prohibition